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Transcriptional remodeling of primary human monocytes exposed to Leishmania braziliensis

ABSTRACT: Trained immunity is a phenomenon whereby innate immune cells such as monocytes or macrophages undergo functional reprogramming after exposure to certain microbial components, altering their responses to future exposures. This study profiled the transcriptome of human monocytes trained with Leishmania braziliensis and then re-exposed to lipopolysaccharide.

ORGANISM(S): Homo sapiens

PROVIDER: GSE211212 | GEO | 2024/03/20

REPOSITORIES: GEO

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