Transcriptomics

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Gene expression profiles at the single cell levels of murine tumor inflitrating PD-1 and PD-1 KO NK cells


ABSTRACT: Here, we found by single cell RNA sequencing analysis that PD-1 can be expressed on MHC class I-deficient tumor-infiltrating NK cells in vivo. We also demonstrate distinct alterations in the phenotype of PD-1-deficient NK cells and a more mature phenotype which might reduce their capacity to migrate and kill in vivo.

ORGANISM(S): Mus musculus

PROVIDER: GSE211488 | GEO | 2022/08/19

REPOSITORIES: GEO

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