Transcriptomics

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RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression [RNA-seq]


ABSTRACT: To investigate the cooperative function NCoR/HDAC3/PGC1β complex in the regulation of osteoclast differentiation, we used NCoR KO or PGC1β KO bone marrow cells and non-coding RNA Dancr/Rnu12 siRNA knockdown bone marrow cells or RAW 264.7 cells. We then performed gene expression profiling analysis using data obtained from RNA-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE211674 | GEO | 2022/08/22

REPOSITORIES: GEO

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