Transcriptomics

Dataset Information

0

RNA-sequencing of WT and P2Y4 KO pericardial adipose tissue (PAT) 24 hours after left anterior descending artery (LAD) ligation


ABSTRACT: We identified differentially regulated genes in the pericardial adipose tissue of wild type (WT) and P2Y4 KO mice, 24 hours after left anterior descending artery (LAD) ligation as a model of myocardial infarction (MI). Differentially regulated genes were involved in metabolism, brown fat cell differentiation, immune response and inflammation. P2Y4 KO mice displayed adipocyte beiging with increased PD-L1 expression and a higher number of regulatory leukocytes in their PAT 24 hours after LAD ligation. Up-regulated genes linked to adipocyte beiging included Ucp1, Cited1 and Prdm16.

ORGANISM(S): Mus musculus

PROVIDER: GSE211768 | GEO | 2022/08/25

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2006-03-24 | GSE4105 | GEO
| PRJNA872095 | ENA
2025-03-28 | GSE289143 | GEO
| PRJNA716506 | ENA
2025-04-10 | GSE278719 | GEO
2021-05-17 | GSE174497 | GEO
| PRJNA622560 | ENA
2018-05-23 | E-MTAB-6796 | ExpressionAtlas
2025-04-10 | GSE278720 | GEO
| WBGene00002243 | ExpressionAtlas