Transcriptomics

Dataset Information

0

The transcriptomic landscape of glutamatergic cortical neurons carrying Alzheimer’s disease PSEN1 mutations reveals alterations in structural components, signalling, and ncRNA regulation


ABSTRACT: To investigate gene expression changes related to two fAD mutations (A79V and L150P) in the Presenilin-1 gene (PSEN1) we compared the transcriptomes (polyA and total) of glutamatergic cortical neurons derived from fAD-mutant human induced pluripotent stem cells and their individual isogenic controls generated via precision CRISPR/Cas9 genome editing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE211993 | GEO | 2023/01/24

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2015-01-20 | E-GEOD-39420 | biostudies-arrayexpress
2015-01-20 | GSE39420 | GEO
2020-02-29 | GSE136894 | GEO
2024-06-20 | GSE253337 | GEO
2020-09-19 | GSE158233 | GEO
2022-12-15 | GSE221027 | GEO
2019-12-31 | GSE138695 | GEO
| PRJEB24858 | ENA
2015-12-05 | E-GEOD-42745 | biostudies-arrayexpress
2021-03-22 | GSE121729 | GEO