Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of human kidney cortex and medulla

ABSTRACT: We report gene expression (RNA-seq) from macro-dissected human kidney cortex and medulla from 3 individuals

ORGANISM(S): Homo sapiens

PROVIDER: GSE212907 | GEO | 2023/11/22

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Chromatin accessibility maps in human kidney cortex and medulla

Project description:We report chromatin accessibility (ATAC-seq) maps from macro-dissected human kidney cortex and medulla from 3 individuals

2023-11-22 | GSE212908 | GEO

RNA-seq of human kidney cortex and medulla

Project description:We report gene expression (RNA-seq) from macro-dissected human kidney cortex and medulla from 3 individuals. The samples were from patients undergoing kidney removal for tumors, but the tissues used in the study itself were normal tissue/cultured cells not involved by tumor.

2022-02-08 | GSE152301 | GEO

Chromatin accessibility maps in human kidney cortex and medulla

Project description:We report chromatin accessibility (ATAC-seq) maps from macro-dissected human kidney cortex and medulla from 3 individuals. The samples were from patients undergoing kidney removal for tumors, but the tissues used in the study itself were normal tissue/cultured cells not involved by tumor.

2022-02-08 | GSE152300 | GEO

Chromatin conformation maps in human kidney cortex and medulla

Project description:We report chromatin conformation (Hi-C) maps from macro-dissected human kidney cortex and medulla from 1 individual

2023-11-22 | GSE212909 | GEO

Chromatin conformation maps in human kidney cortex and medulla from a diabetic donor

Project description:We report chromatin conformation (Hi-C) maps from macro-dissected human kidney cortex and medulla from 1 individual

2023-11-22 | GSE242141 | GEO

The effect of cortex/medulla proportions on molecular diagnoses in kidney transplant biopsies: rejection and injury can be assessed in medulla

Project description:Histologic assessment of kidney transplant biopsies relies on cortex rather than medulla, but for microarray studies, the proportion cortex in a biopsy is typically unknown and could affect the molecular readings. The present study aimed to develop a molecular estimate of proportion cortex in biopsies and examine its effect on molecular diagnoses. Microarrays from 26 kidney transplant biopsies divided into cortex and medulla components and processed separately showed that many of the most significant differences were in glomerular genes e.g. NPHS2, NPHS1, CLIC5, PTPRO, PLA2R1, PLCE1, PODXL and REN. Using NPHS2 (podocin) to estimate proportion cortex, we examined whether proportion cortex influenced molecular assessment in the Molecular Microscope Diagnostic System. In 1190 unselected kidney transplant indication biopsies (Clinicaltrials.govNCT01299168), only 11% had <50% cortex. Molecular scores for ABMR, TCMR, and injury were independent of proportion cortex. Rejection was diagnosed in many biopsies that were mostly or all medulla. Agreement in molecular diagnoses in paired cortex/medulla samples (23/26) was similar to biological replicates (32/37). We conclude that NPHS2 expression can estimate proportion cortex; that proportion cortex has little influence on molecular diagnosis of rejection, and that, although histology cannot assess medulla, rejection does occur in medulla as well as cortex.

2017-04-27 | GSE95611 | GEO

The effect of cortex/medulla proportions on molecular diagnoses in kidney transplant biopsies: rejection and injury can be assessed in medulla

2017-04-27 | E-GEOD-95611 | biostudies-arrayexpress

RNA-seq of human kidney cortex and medulla

Project description:RNA-seq of human kidney cortex and medulla

| PRJNA638927 | ENA

RNA-seq of human kidney cortex and medulla

Project description:RNA-seq of human kidney cortex and medulla

| PRJNA878298 | ENA

Chromatin accessibility maps in human kidney cortex and medulla

Project description:Chromatin accessibility maps in human kidney cortex and medulla

| PRJNA638928 | ENA