Transcriptomics

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Characterization of Directly Regulated Thyroid Hormone Mediated Gene Expression Following Short-Term Perturbations in Thyroid Hormone Levels in Juvenile Mice


ABSTRACT: We investigated the effects of thyroid hormone disruptions on gene expression in juvenile mice liver to develop a stronger understanding of the mechanisms by which thyroid disrupting chemicals impair development. Gene expression was examined by hybridization of hepatic RNA to Agilent mouse microarrays for hyper-, hypo-, hypo-replacement (hypo+) and euthyroid animals. Keywords: Toxicogenomics, biomarkers of thyroid disruptors

ORGANISM(S): Mus musculus

PROVIDER: GSE21307 | GEO | 2012/03/30

SECONDARY ACCESSION(S): PRJNA126557

REPOSITORIES: GEO

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