Effect of hematopoietic-specific heterozygous loss of Dnmt3a on the molecular pathophysiology of colitis-associated colon cancer (CAC) in a mouse model
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ABSTRACT: To model clonal hematopoiesis driven by DNMT3A loss-of-function, bone marrow chimerae with Dnmt3a(+/-) (experiment) or Dnmt3a(+/+) (control) were established in C57BL6/J wt mice, followed by standard CAC induction by AOM/DSS
ORGANISM(S): Mus musculus
PROVIDER: GSE213178 | GEO | 2023/06/12
REPOSITORIES: GEO
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