Prolonged sleep deprivation induces cytokine storm-like syndrome in mammals [scRNA-Seq]
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ABSTRACT: Sleep is deeply involved in neuroimmune regulation, while the mechanism is yet to be elucidated. Experimental manipulation of sleep duration provides a reliable measure for evaluating how sleep regulates innate immunity. Here we report a modified sleep deprivation paradigm (SD) that can constantly awaken the mice with more than 95% efficiency, and investigate the effects of prolonged sleep deprivation on mice's immune systems.
ORGANISM(S): Mus musculus
PROVIDER: GSE213496 | GEO | 2023/11/27
REPOSITORIES: GEO
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