RNA-sequencing shows the changes on transcriptomes after deletion of Setd2 in VHL deficient mice.
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ABSTRACT: To explore the possible role of SETD2 in renal fibrosis formation, we generated VHL-KO and VHL-KO; SETD2-KO mice with a transgenic Ksp1.3/Cre mouse line. To get an insight into the mechanism of how SETD2 deletion promotes renal fibrogenesis in the absence of VHL, we performed RNA-seq using the renal tubules isolated from VHL-KO and VHL -KO; SETD2-KO mice
ORGANISM(S): Mus musculus
PROVIDER: GSE213922 | GEO | 2022/10/19
REPOSITORIES: GEO
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