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Surviving the host: microbial metabolic genes required for growth of Pseudomonas aeruginosa in physiologically-relevant conditions

ABSTRACT: Here, we used a saturated transposon insertion mutant pool of P. aeruginosa strain PAO1 and transposon insertion sequencing (Tn-Seq), to identify genes conditionally important for survival under conditions mimicking the environment of a nosocomial infection. Conditions tested included tissue culture medium with and without human serum, a murine abscess model, and a human skin organoid model.

ORGANISM(S): Pseudomonas aeruginosa PAO1

PROVIDER: GSE214167 | GEO | 2022/11/04

REPOSITORIES: GEO

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| S-EPMC9732424 | biostudies-literature

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