Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Accelerated Epigenetic Aging and DNA Methylation Alterations in Berardinelli-Seip Congenital Lipodystrophy

ABSTRACT: Genome wide DNA methylation profiling of Congenital Lipodystrophy type 2 patients, mutation carriers , and healthy control samples .The Infinium MethylationEPIC Kit was used to measure genome-wide DNA methylation across > 868,000 CpG sites.

ORGANISM(S): Homo sapiens

PROVIDER: GSE214297 | GEO | 2023/08/08

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Accelerated Epigenetic Aging and DNA Methylation Alterations in Berardinelli-Seip Congenital Lipodystrophy

Project description:Accelerated Epigenetic Aging and DNA Methylation Alterations in Berardinelli-Seip Congenital Lipodystrophy

| PRJNA884841 | ENA

EPIC analysis of Brazilian babies born with congenital microcephaly

Project description:Genome-wide DNA methylation profiling of over 850,000 methylation sites carried out using the Illumina MethylationEPIC BeadChip was used to compare 18 babies born with congenital Zika virus microcephaly, 7 babies exposed to Zika virus in utero but born without clinical signs, and 20 control unexposed unaffected babies

2020-07-20 | GSE145233 | GEO

mRNA-seq read counts of peripheral blood mononuclear cells from congenital generalized lipodystrophy patients and their gender/aged-matched controls

Project description:Congenital generalized lipodystrophy (CGL) is an autosomal recessive disorder characterized by defective adipose tissue, extreme insulin resistance, and early onset of diabetes. There are four types of congenital generalized lipodystrophy based on the causative genetic alterations. The symptoms and the degrees of disease progression are varied among all affected individuals, which might be due to unknown genetic modifiers. To identify potential predictive biomarkers associated with the disease progressions, we recruited 7 patients (cgl2_p1,cgl2_p2,cgl2_p3,cgl2_p4,cgl2_p5,cgl2_p6,cgl2_p7),as well as gender/aged-matched controls (cgl2_c1,cgl2_c2,cgl2_c3,cgl2_c4,cgl2_c5,cgl2_c6,cgl2_c7).The total RNA samples were extracted from the participants' peripheral blood mononuclear cells, followed by RNA-Seq. To find the molecular signatures that might be associated with disease progression, patients were further categorized into sub-groups based on the results of biochemical analysis and their clinical symptoms (e.g. diabetes, metabolic syndrome and metal retardation). DEGs were identified for each sub-groups of patients, and pathway analysis was performed to explore the underlying dysregulated mechanisms.

2021-08-18 | GSE159337 | GEO

Impaired signaling pathways on Berardinelli–Seip congenital lipodystrophy macrophages during Leishmania infantum infection

Project description:Impaired signaling pathways on Berardinelli–Seip congenital lipodystrophy macrophages during Leishmania infantum infection

| PRJNA866148 | ENA

Genome-wide DNA methylation status of scirrhous CAF, non-scirrhous CAF, and GIST fibroblast

Project description:Genome-wide DNA methylation was analyzed using the Infinium Human MethylationEPIC BeadChip.

2022-03-01 | GSE194259 | GEO

Analysis of DNA methylation-based tumor immune microenvironment patterns in metastatic melanoma

Project description:We subjected 196 melanoma tumors to genome-wide methylation analysis using the Illumina Infinium MethylationEPIC BeadChip array.

2020-03-25 | GSE144487 | GEO

Epigenome analysis of samples from oral cancer and oral leukoplakias patients

Project description:Genome wide DNA methylation profiling in oral cancer and oral leukoplakia patients. The cohort included 48 patients in total, with control, oral leukoplakia patients and oral cancer patients. The Infinium MethylationEPIC BeadChips 850K has been used to interrogate DNA methylation changes.

2022-09-30 | E-MTAB-12202 | biostudies-arrayexpress

Differential DNA methylation and changing cell type proportions as fibrotic stage progresses in NAFLD

Project description:Genome wide DNA methylation profiling of normal and NAFLD liver samples. The Illumina Infinium MethylationEPIC BeadChip kit was used to obtain DNA methylation profiles across CpGs.

2021-07-23 | GSE180474 | GEO

DNA Methylation Signatures in Blood DNA of Hutchinson Gilford Progeria Syndrome

Project description:Genome wide DNA methylation profiling of 12 control and 15 progeroid laminopahties samples. The Infinium MethylationEPIC Kit was used to measure DNA methylation across approximately 868,564 CpG sites.

2022-02-15 | GSE182991 | GEO

Epigenome analysis of cutaneous squamous cell carcinoma samples

Project description:Genome wide DNA methylation profiling in cutaneous squamous cell carcinoma. The Infinium MethylationEPIC BeadChips 850K has been used to interrogate DNA methylation changes. The cohort included 23 patients in total, with precursors of squamous cell carcinoma (actinic keratosis group) and with cSCC at different stages.

2019-12-12 | E-MTAB-8542 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data