Transcriptomics

Dataset Information

0

RNA‐seq of comprehensively examine variations in MHCC-97H cells treated with various doses of lenvatinib at the transcriptomic level.


ABSTRACT: To determine the drug target of lenvatinib, RNAseq was used to evaluate the transcriptome differences between lenvatinib-treated MHCC-97H cells and their parental counterparts.Results show that SERPINE1 may be direct target of lenvatinib, and AKR1C1 have potential prognostic significance in the prediction of LR(lenvatinib-resistant) in HCC. AKR1C1 could be a promising therapeutic target for patients with LR-type liver cancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE214324 | GEO | 2022/11/01

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-06-19 | GSE122145 | GEO
| PRJNA884761 | ENA
2022-08-26 | GSE211850 | GEO
2019-02-12 | GSE97387 | GEO
2018-11-29 | GSE123039 | GEO
| PRJNA507372 | ENA
2023-08-08 | GSE223201 | GEO
2023-09-27 | GSE218010 | GEO
2021-07-22 | GSE157905 | GEO
2022-12-24 | GSE192912 | GEO