Antitumor immunity induced by antibody-based natural killer cell engager therapeutics armed with not-alpha IL-2 variant
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ABSTRACT: We report here the design of new antibody-based natural killer cell engager therapeutics (ANKET), single tetraspecific molecules engaging the NK cell activating receptors NKp46 and CD16, the β chain of the interleukin-2 receptor (IL-2R) and a tumor-associated antigen (TAA).
ORGANISM(S): Homo sapiens
PROVIDER: GSE214378 | GEO | 2022/10/05
REPOSITORIES: GEO
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