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BLM deficiency affects cytotoxicity of temozolomide and olaparib against human glioma cells and induces cellular senescence or polyploidy

ABSTRACT: BLM deficient cells responded differently to the temozolomide and olaparib treatment in comparison to the wild type cells. The double treatment evoked cell cycle arrest, cellular senescence or polyploidy in BLM KO LN229 and LN18 cells, respectively.

ORGANISM(S): Homo sapiens

PROVIDER: GSE214931 | GEO | 2023/05/17

REPOSITORIES: GEO

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