Transcriptomics

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Hypothermic oxygenated machine perfusion promotes mitophagy flux against hypoxia ischemic injury in donation after circulatory death liver


ABSTRACT: HOPE is a dynamic preservation method to attenuate IRI in DCD liver. In a rat model of DCD liver, the protective mechanism of HOPE is probably by promoting mitophagy flux in response to hypoxia-ischemic injury. We performed gene expression profiling analysis using data obtained from RNA-seq of 4 different groups in DCD liver.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE215134 | GEO | 2022/10/15

REPOSITORIES: GEO

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