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Expression data comparing osimertinib-resistant H1975 and PC-9 cells, and cells that survive after treatment of those cells with a PAI-1 inhibitor

ABSTRACT: Even after osimertinib is administered to lung adenocarcinomas with EGFR mutations, there are a few cells which survive, and these tolerant cells are considered to be the source of later recurrence. We suspect that PAI-1 is involved in the regulation of these resistant cells and are currently investigating the role of PAI-1 in this process. We used microarray analysis to explore mechanisms involving PAI-1 behind the tolerance to osimertinib in lung adenocarcinoma cells with EGFR mutations.

ORGANISM(S): Homo sapiens

PROVIDER: GSE216149 | GEO | 2022/10/21

REPOSITORIES: GEO

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