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Immune Infiltration in Aggressive Papillary Craniopharyngioma: High infiltration But Low Action

ABSTRACT: Papillary craniopharyngiomas (PCPs) are biologically benign but clinically aggressive lesions hence affect the quality of life. The expression of inflammatory mediators and regulation of the immune microenvironment in PCPs have not been investigated much. In this study, for the first time, we assessed the immune cell infiltration and immune cell signatures in PCPs by analyzing the bulk-RNA sequencing data. Our results indicated that PCPs are in a state of high immune infiltration but low action with abundant inflammatory cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE216330 | GEO | 2022/10/28

REPOSITORIES: GEO

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