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Effect of SAP30 in breast cancer progression and metastasis (RNA-Seq)

ABSTRACT: To investigate the cooperative function of SAP30/SIN3A(SIN3B)/MLL1 complex in breast cancer progression and metastasis, we established SAP30-KO, SIN3A+SIN3B-DKO and MLL1-KO MDA-MB-231 cells by CRISPR-Cas9. We then performed gene expression profiling analysis using data obtained from RNA-seq of the parental cells as well as each KO cell line. Two biological repeats were applied for each cell line.

ORGANISM(S): Homo sapiens

PROVIDER: GSE216345 | GEO | 2023/09/14

REPOSITORIES: GEO

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