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ACUTE BLEEDING AND STORED RED BLOOD CELLS TRANSFUSION ATTENUATES LIVER REGENERATION FOLLOWING PARTIAL HEPATECTOMY

ABSTRACT: Our aim was to study the impact of bleeding and red blood cell (RBC) resuscitation on liver regeneration. We assessed the impact of RBC storage time on liver regeneration following 50% partial hepatectomy (PHx) in rats, and explored possible contributing molecular mechanisms using immunohistochemistry, RNA-Seq, and macrophage depletion.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE216924 | GEO | 2022/11/14

REPOSITORIES: GEO

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