Transcriptomics

Dataset Information

0

Effect of miR-27a-5p on SGBS adipogenesis


ABSTRACT: We have recently confirmed miR-27a-3p as a crucial regulator of human adipogenesis (Wu H, Pula T, Tews D, Amri E-Z, Debatin K-M, Wabitsch M, Fischer-Posovszky P, Roos J. microRNA-27a-3p but Not -5p Is a Crucial Mediator of Human Adipogenesis. Cells. 2021; 10(11):3205. https://doi.org/10.3390/cells10113205 ). MiR-27a-5p did not impair human adipogenesis. However, since several publications state that miR-27a ist also a crucial regulator of UCP1, we were interested if miR-27a-3p or miR-27a-5p regulatas UCP1 and other thermogenesis related genes. We found a strong regulation of UCP1 with functional relevance for the cellular metabolism by miR-27a-5p.To asesse the mRNA gene expression pattern, mRNA sequencing was performed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE217629 | GEO | 2024/06/30

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2014-06-01 | E-GEOD-48006 | biostudies-arrayexpress
2022-07-07 | GSE197085 | GEO
2024-06-13 | PXD037862 | Pride
2024-06-13 | PXD037998 | Pride
| EGAD00001006844 | EGA
2017-05-11 | GSE98769 | GEO
| EGAD00001006842 | EGA
2014-06-01 | GSE48006 | GEO
2023-11-28 | GSE189959 | GEO
2023-05-10 | PXD036109 | Pride