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RNA-seq reveals an abnormal transcriptome as a result of DDX20 loss in spermatogonia.

ABSTRACT: To investigate the role of DDX20 in spermatogenesis, we generated Ddx20 flox/flox Ddx4-Cre mice to make a germ cell-specific Ddx20 knockout, and isolated spermatogonia from four-day-old mouse testes by THY1 magnetic beads.We then performed gene expression profiling analysis using data obtained from RNA-seq of THY1 + spermatogonia.

ORGANISM(S): Mus musculus

PROVIDER: GSE217685 | GEO | 2023/10/01

REPOSITORIES: GEO

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