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Single-cell RNA-sequencing of human lung monocytes and macrophages from MISTRG mice on day 21 or day 36 post-transplantation with human CD34+ hematopoietic stem and progenitor cells (HSPCs)

ABSTRACT: The ontogeny of human lung macrophages derived from blood monocytes is poorly understood. In this study, we employed single-cell RNA-sequencing to investigate the heterogeneity of HSPC-derived human lung monocytes and macrophages in the MISTRG humanized mouse model.

ORGANISM(S): Homo sapiens

PROVIDER: GSE217722 | GEO | 2022/11/11

REPOSITORIES: GEO

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Single-cell RNA-sequencing of human lung monocytes and macrophages from MISTRG mice on day 21 or day 36 post-transplantation with human CD34+ hematopoietic stem and progenitor cells (HSPCs)

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