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Map active enhancer and gene promoter regions in the SCN

ABSTRACT: Histone ChIP-seq was performed at varied time of the day to map the gene promoter and active enhancer sites in the central clock; SCN (suprachiasmatic nuclei). Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for the histone modifications H3K4me3 and H3K27ac in adult mouse SCN and cortex at distinct time of the day .

ORGANISM(S): Mus musculus

PROVIDER: GSE217941 | GEO | 2023/04/24

REPOSITORIES: GEO

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Mouse SCN in LC-MSMS - The suprachiasmatic nucleus (SCN) acts as the central clock to coordinate circadian oscillations in mammalian behavior, physiology and gene expression. Despite our knowledge of the circadian transcriptome of the SCN, how it impacts genome-wide protein expression is not well understood. Here, we interrogated the murine SCN proteome across the circadian cycle using SILAC-based quantitative mass spectrometry.

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Map active enhancer and gene promoter regions in the SCN

Project description:Map active enhancer and gene promoter regions in the SCN

| PRJNA901441 | ENA

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