Transcriptomics

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S. coelicolor LY2517 R5- medium time course study (Culture # 2)


ABSTRACT: Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study, we employed whole-genome microarrays to investigate the temporal transcriptome profiles of S. coelicolor A3(2) deltaSCO2517::kan mutant strain (LY2517) and compare it to the wild-type M145 strain. SCO2517 is a putative two-component system response regulator.

ORGANISM(S): Streptomyces coelicolor

PROVIDER: GSE21810 | GEO | 2012/12/19

SECONDARY ACCESSION(S): PRJNA129347

REPOSITORIES: GEO

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