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Single cell seq of E13.5 and E15.5 pancreas of Setd2 WT and KO mice [scRNA-seq]

ABSTRACT: To observe the difference in fetal pancreas between Setd2 WT and KO mice, we performed single cell seq to elucidate the discrapency.

ORGANISM(S): Mus musculus

PROVIDER: GSE218739 | GEO | 2023/12/22

REPOSITORIES: GEO

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Single cell seq of E13.5 and E15.5 pancreas of Setd2 WT and KO mice [scRNA-seq]

Project description:Single cell seq of E13.5 and E15.5 pancreas of Setd2 WT and KO mice [scRNA-seq]

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Project description:Jarid2, a member of the Jumanji family of proteins, is a developmental regulator that is necessary for proper mouse development and stem cell differentiation. To investigate the specific functions of Jarid2 during pancreas development, we generated pancreas-specific Jarid2 mutants. We used microarrays to determine gene expression changes resulting from deletion of the Jarid2 gene in the pancreas.

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