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Effect of depletion of Suv39h1 on gene expression of TGF-β stimulated mouse primary renal fibroblasts

ABSTRACT: To investigate the the role of suv39h1 in the regulation of kidney fibrosis in vitro, we established suv39h1fl/fl mice and isolated renal fibroblasts.Fibroblasts were treated with Cre recombinant adenovirus (Ad-Cre) or GFP recombinant adenovirus(Ad-GFP) , and then TGF-β was added to the cells after starving overnight.

ORGANISM(S): Mus musculus

PROVIDER: GSE218814 | GEO | 2023/11/01

REPOSITORIES: GEO

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