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Finding genetic loci that are sensitive to demethylation to assist in the development of DNA methylation-based in vitro assay for the identification of carcinogens

ABSTRACT: Purpose: To use reduced representation bisulfite sequencing and RNA-seq to identify demethylated promoters of genes that were derepressed following treatment with demethylating agent, 5-Aza-2'-deoxycytidine (5aCdR, CAS# 2353-33-5).

ORGANISM(S): Mesocricetus auratus Homo sapiens

PROVIDER: GSE218911 | GEO | 2023/02/10

REPOSITORIES: GEO

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