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Dynamic redistribution of CTCF demarcates bifurcation of cytotoxic effector and memory precursor programs [Hi-C]

ABSTRACT: CTCF is known to mediate long range chromatin intearction and 3D genome organization. In CD8+ T cells responding to actue infection, CTCF is redistributed to induce the the cytotoxic program while using its insulation function to suppresss memory precursor fate.

ORGANISM(S): Mus musculus

PROVIDER: GSE220528 | GEO | 2023/02/03

REPOSITORIES: GEO

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