Measuring the effect of deoxycholate on Bacteroides fragilis gene expression

ABSTRACT: We used RNAseq as an approach to assess the B. fragilis strain p207 response to the bile salt, deoxycholic acid (DC). A 6min DC exposure dramatically remodeled the transcriptome with approximately 20% of transcripts exhibiting significant changes. Chaperones and efflux systems were among the most highly induced genes, while protein synthesis genes were strongly repressed by DC.

ORGANISM(S): Bacteroides fragilis

PROVIDER: GSE220692 | GEO | 2023/08/01

REPOSITORIES: GEO