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Epigenetic and metabolic reprogramming by HDAC inhibition targets NRF2-active tumors [CUT&Tag]

ABSTRACT: To investigate the NRF2-specific cytotoxic effects of HDAC inhibition, we assessed genomic distribution of histone acetylation modifications and readers in the context of control and NRF2-overexpressing mouse LUAD cells upon HDAC inhibition.

ORGANISM(S): Mus musculus

PROVIDER: GSE220832 | GEO | 2023/03/30

REPOSITORIES: GEO

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