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Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice [genomicDNA]

ABSTRACT: We assessed genome editing strategies to treat cardiomyopathy in mice including one or two doses of ABE8e, or one low, medium, or high dose of SaCas9 nuclease We conducted RNA analysis and genomic DNA analysis at the target region and transcriptome-wide analysis to assess cellular phenotypes

ORGANISM(S): Mus musculus

PROVIDER: GSE220850 | GEO | 2022/12/13

REPOSITORIES: GEO

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Efficient in vivo Genome Editing Prevents Hypertrophic Cardiomyopathy in Mice [Amplified_cDNA]

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Project description:This SuperSeries is composed of the SubSeries listed below.

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