Transcriptomics

Dataset Information

0

Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [MCF10A]

ABSTRACT: The functions of MYC acetylation have remained unclear. In this study we identified the major lysine residues of MYC that are acetylated by p300 and GCN5 in cancer cell lines and established the requirment of three specific acetyl-lysine (AcK) residues for MYC transformation of Rat1a fibroblasts and MCF10 mammary epithelial cells. We further uncovered gene-selective regulatory functions and conserved genetic programs and biolofical processes regulated by MYC AcK residues in both cell types.

ORGANISM(S): Homo sapiens

PROVIDER: GSE220918 | GEO | 2024/03/20

REPOSITORIES: GEO

Json Xml

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

Transcriptomics Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [Rat1A]
2024-03-20 | GSE220919 | GEO
Genomics Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [MCF10A]
| PRJNA912073 | ENA
Genomics Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation
| PRJNA911991 | ENA
Genomics Role of MYC acetylated lysine residues in cell transformation and gene-selective regulation [Rat1A]
| PRJNA912074 | ENA
Proteomics The acetylated lysine residues of AdhE
2021-09-08 | PXD028234 |
Proteomics The acetylated lysine residues of Pta
2021-09-08 | PXD028235 |
Proteomics The acetylated lysine residues in C. ljungdahlii
2021-09-08 | PXD028233 |
Proteomics The acetylated lysine residues of Acs (TPA&control)
2022-02-14 | PXD031674 |
Proteomics The acetylated lysine residues of RNase II (TPA&control)
2022-02-14 | PXD031675 |
Genomics Mapping of H4-acetylated chromatin modifications in differentiating human primary myoblasts
2006-08-28 | GSE4132 | GEO