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PIKFYVE Inhibition Mitigates Disease in Models of Diverse Forms of ALS [2]

ABSTRACT: RNA sequencing analysis of human iPSC-derived motor neurons generated from two C9ORF72 ALS/FTD patient lines, treated with negative control ASO (NC ASO) or PIKFYVE ASO. The goal of this study is to evaluate the effect of PIKFYVE suppression in rescuing ALS motor neuron degeneration.

ORGANISM(S): Homo sapiens

PROVIDER: GSE221016 | GEO | 2022/12/18

REPOSITORIES: GEO

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PIKFYVE Inhibition Mitigates Disease in Models of Diverse Forms of ALS [1]

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