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Global gene expression profile of CNS-infiltrating E2A-PBX1+/preBCR+ ALL cells

ABSTRACT: In order to elucidate mechanism of resistance to BTKi and dasatinib in CNS-infiltrating leukemia cells and to investigate the CNS homing of E2A-PBX1/preBCR+ ALL cells, we performed global transcriptome analysis by RNA sequencing. RNA was isolated from CNS-infiltrating cells from vehicle, dasatinib, ibrutinib, dasatinib + ibrutinib-treated mice

ORGANISM(S): Mus musculus

PROVIDER: GSE221238 | GEO | 2024/03/15

REPOSITORIES: GEO

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