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Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression which can only be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signalling

ABSTRACT: We investigated how Interleukin 1 beta impacts equine tenocyte function and global gene expression in 3D culture and determined if these effects could be rescued by pharmacologically inhibiting nuclear factor-κB or interleukin 1 signalling.

ORGANISM(S): Equus caballus

PROVIDER: GSE221370 | GEO | 2023/06/14

REPOSITORIES: GEO

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Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression which can only be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signalling

Project description:Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression which can only be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signalling

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