Transcriptomics

Dataset Information

0

ALYREF Mediates RNA m5C Modification to Promote Hepatocellular Carcinoma Progression


ABSTRACT: The RNA methyltransferase Aly/REF export factor (ALYREF) is considered one type of “reader” protein located in the nucleus that recognizes and binds directly with m5C sites in RNA and facilitates the export of RNA from the nucleus to the cytoplasm. Notably, ALYREF is considered a promising target for diagnosis and prognosis prediction. However, until now, the low number of related studies has limited the understanding of the mechanism of the HCC-promoting effects of ALYREF. To further elucidate the oncogenic roles of ALYREF in hepatocellular carcinoma (HCC), we assessed the expression levels of ALYREF in clinical samples and HCC cell lines and explored the effects of ALYREF deficiency by both in vitro experiments and m5C-methylated RNA immunoprecipitation sequencing (m5C-MeRIP-Seq)

ORGANISM(S): Homo sapiens

PROVIDER: GSE221793 | GEO | 2023/03/22

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-09-29 | PXD035761 | Pride
2020-04-14 | GSE139606 | GEO
2017-05-19 | GSE99069 | GEO
2019-02-27 | GSE124735 | GEO
2014-02-20 | E-GEOD-53370 | biostudies-arrayexpress
2023-08-11 | GSE199874 | GEO
2022-02-05 | GSE195701 | GEO
2013-09-27 | E-GEOD-49658 | biostudies-arrayexpress
2024-10-01 | GSE278327 | GEO
2022-04-29 | MSV000089337 | MassIVE