Transcriptomics

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Single-Cell ATAC+RNAseq from CD34+ cells of a Primary Myelofibrosis patient evolved to secondary Acute Myeloid Leukemia


ABSTRACT: To characterize the impact of chromatin remodelers’ mutations in MPN onset and development and identify regulatory elements driving gene expression modulations during disease progression, we performed a single-nucleus RNAseq coupled with single-cell ATACseq experiment on CD34+ cells from the chronic and blast phase of a Primary Myelofibrosis patient.

ORGANISM(S): Homo sapiens

PROVIDER: GSE221946 | GEO | 2024/04/29

REPOSITORIES: GEO

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