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Mycobacterial DNA binding protein 1 (MDP1) mediates gene regulation in Mycobacterium tuberculosis variant Bacillus Calmette-Guerin

ABSTRACT: To investigate the role of MDP1 in global transcription regulation, we established MDP1 conditional knockdown BCG using CRISPR/dCas9 system. Transcriptome profiling was then performed using data obtained from RNA-seq of two BCG MDP1 mutants compared to the vector control at three growth time points.

ORGANISM(S): Mycobacterium tuberculosis variant bovis

PROVIDER: GSE222247 | GEO | 2023/08/01

REPOSITORIES: GEO

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