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Zfp352 and Zfp352+Dux over expression chip-seq result

ABSTRACT: Our data delineated bifurcated binding and regulation of ZFP352 towards two distinct retrotransposons, MT2_Mm and SINE_B1/Alu,further ChIP-seq experiments validated that over-expression of Dux displaced ZFP352 from SINE_B1/Alu and DUX-independent ZFP352 binding sites, but promoted ZFP352 binding onto MT2_Mm and DUX_ZFP352 co-bound sites

ORGANISM(S): Mus musculus

PROVIDER: GSE222634 | GEO | 2023/06/01

REPOSITORIES: GEO

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Zfp352 over expression ATAC-seq result

Project description:Our data delineated bifurcated binding and regulation of ZFP352 towards two distinct retrotransposons, MT2_Mm and SINE_B1/Alu,and whether ZFP352 can regulate mouse genome openness remains unknown,here we conduct ATAC-seq of Zfp352 over expression sample to detect ZFP352's role in regulating chromatin openness.

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Zfp352 and Zfp352+Dux over expression chip-seq result

Project description:Zfp352 and Zfp352+Dux over expression chip-seq result

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Zfp352 over expression chip-seq result

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Zfp352 over expression ATAC-seq result

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