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Mac-1 marks a quiescent and functionally superior HSC subset during regeneration

ABSTRACT: Here, we assessed the expression of Mac-1 on mouse HSCs during regeneration following transplantation and observed a transient increase in Mac-1 expression during the early reconstitution phase. Serial transplantation experiments demonstrated that reconstitution potential was highly enriched in the Mac-1+ portion of the HSC pool.

ORGANISM(S): Mus musculus

PROVIDER: GSE223648 | GEO | 2023/03/02

REPOSITORIES: GEO

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MAC-1 marks a quiescent and functionally superior HSC subset during regeneration.

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