Mammalian Methylation Consortium

ABSTRACT: The Mammalian Methylation Consortium aimed to characterize the relationship between cytosine methylation levels and a) species characteristics such as maximum lifespan and b) individual sample characteristics such as age, sex, tissue type. Both supervised machine learning approaches and unsupervised machine learning approaches were applied to the data as described in the citations. To facilitate comparative analyses across species, the mammalian methylation consortium applied a single measurement platform (the mammalian methylation array, GPL28271) to n=15216 DNA samples derived from 70 tissue types of 348 different mammalian species (331 eutherian-, 15 marsupial-, and 2 monotreme species). Most of the CpGs are located in highly conserved stretches of DNA but not all CpGs apply to all species as detailed in the description of the platform, GPL28271 and on https://github.com/shorvath/MammalianMethylationConsortium/.

ORGANISM(S): Equus asinus somalicus Sciurus niger Tupaia gracilis Delphinapterus leucas Parascalops breweri Nesogale talazaci Cavia tschudii Oryctolagus cuniculus Sorex trowbridgii Peromyscus maniculatus Lasiopodomys mandarinus Ovis aries Cuniculus paca Mustela altaica Tragelaphus angasii Scalopus aquaticus Phyllostomus hastatus Sorex caecutiens Notamacropus agilis Callospermophilus lateralis Mus minutoides Rhinopoma hardwickii Propithecus tattersalli Meriones libycus Tupaia longipes Rhinolophus alcyone Pongo pygmaeus Cryptomys hottentotus Hemicentetes semispinosus Megaptera novaeangliae Chrysocyon brachyurus Choloepus didactylus Canis latrans Propithecus diadema Saccopteryx bilineata Nanger granti Atelerix albiventris Ochotona hyperborea Myotis brandtii Macroscelides proboscideus Myotis thysanodes Muntiacus vaginalis Balaenoptera musculus Cervus elaphus Loxodonta africana Hapalemur griseus Myotis lucifugus Delphinus delphis Tragelaphus eurycerus Sylvilagus floridanus Amblysomus hottentotus Nycticeius humeralis Ceratotherium simum simum Microgale drouhardi Tragelaphus imberbis Hydrochoerus hydrochaeris Marmota monax Ursus americanus Bos taurus Enhydra lutris Apodemus agrarius Bradypus variegatus Rhynchonycteris naso Sorex hoyi Notamacropus rufogriseus Pteropus hypomelanus Tamandua mexicana Capreolus capreolus Globicephala macrorhynchus Giraffa camelopardalis Chinchilla lanigera Varecia variegata Rattus rattus Sorex vagrans Cricetomys gambianus Sus scrofa Ondatra zibethicus Galeopterus variegatus Choloepus hoffmanni Mus musculus Pipistrellus pipistrellus Oreamnos americanus Dromiciops gliroides Cephalorhynchus hectori hectori Microgale cowani Clethrionomys gapperi Sylvilagus audubonii Dipus sagitta Neophoca cinerea Ochotona alpina Myotis evotis Notamacropus eugenii Aepyceros melampus Sorex tundrensis Papio hamadryas Heterocephalus glaber Peromyscus eremicus Gazella leptoceros Sorex cinereus Myotis vivesi Cabassous unicinctus Suncus varilla Talpa occidentalis Nothocricetulus migratorius Jaculus jaculus Myodes rufocanus Sus scrofa domesticus Ctenomys steinbachi Phocoena phocoena Suricata suricatta Eulemur flavifrons Phodopus roborovskii Hystrix cristata Balaenoptera borealis Napaeozapus insignis Cervus canadensis Crocuta crocuta Neogale vison Phyllostomus discolor Antidorcas marsupialis Galea musteloides Vulpes vulpes Eulemur fulvus Marmota flaviventris Cheirogaleus medius Artibeus jamaicensis Tenrec ecaudatus Aonyx cinereus Mesocricetus auratus Eulemur sanfordi Trichechus manatus Sylvilagus bachmani Okapia johnstoni Pan troglodytes Alticola barakshin Tamias townsendii Orycteropus afer Eulemur albifrons Procavia capensis Crocidura cyanea Mustela frenata Echinops telfairi Eulemur fulvus collaris Hippotragus equinus Neurotrichus gibbsii Ctenomys opimus Sciurus carolinensis Elephas maximus Tupaia belangeri Blarina brevicauda Tursiops truncatus Martes americana Eozapus setchuanus Sorex minutissimus Meriones unguiculatus Orcinus orca Cricetulus griseus Glaucomys sabrinus Nannospalax galili Nycticebus coucang Castor canadensis Bathyergus suillus Urocitellus columbianus Callithrix geoffroyi Canis lupus familiaris Erinaceus europaeus Perodicticus potto Dendrohyrax arboreus Elephantulus edwardii Georychus capensis Microcebus murinus Apodemus peninsulae Equus quagga Callithrix jacchus Cynopterus brachyotis Lepus californicus Nannospalax ehrenbergi Connochaetes taurinus albojubatus Leptonycteris yerbabuenae Ctenomys lewisi Eulemur rufus Molossus molossus Addax nasomaculatus Rhinolophus ferrumequinum Rattus norvegicus Rhabdomys pumilio Ictidomys tridecemlineatus Gerbillus cheesmani Homo sapiens Puma concolor Dasypus novemcinctus Mirza zaza Sylvilagus brasiliensis Alexandromys oeconomus Myotis nattereri Scapanus orarius Peromyscus leucopus Microtus guentheri Macropus fuliginosus Equus caballus Tupaia tana Rhinoceros unicornis Lycaon pictus Ochotona pallasi Setifer setosus Cavia aperea Myocastor coypus Sylvilagus nuttallii Microtus richardsoni Tachyglossus aculeatus Tadarida brasiliensis Tragelaphus strepsiceros Felis catus Eumetopias jubatus Cephalorhynchus hectori maui Tragelaphus spekii Cricetulus barabensis Alexandromys fortis Tragelaphus oryx Acomys cahirinus Neomys fodiens Alexandromys mongolicus Phodopus campbelli Alexandromys maximowiczii Galea musteloides leucoblephara Chaetophractus villosus Callospermophilus saturatus Eulemur mongoz Diceros bicornis Chlorocebus sabaeus Odobenus rosmarus divergens Didelphis virginiana Macropus giganteus Smutsia temminckii Rhombomys opimus Eulemur rubriventer Desmodus rotundus Suncus murinus Stenocranius gregalis Physeter macrocephalus Eulemur macaco Eudorcas thomsonii Capra hircus Acinonyx jubatus Ochotona dauurica Myotis yumanensis Tursiops aduncus Galago moholi Lagenorhynchus albirostris Lepus americanus Neotoma cinerea Kobus megaceros Daubentonia madagascariensis Steno bredanensis Tamandua tetradactyla Zapus princeps Erethizon dorsatum Lasiopodomys brandtii Microtus pennsylvanicus Trachypithecus francoisi Cephalorhynchus commersonii Vombatus ursinus Tolypeutes matacus Ochotona rufescens Ochotona princeps Loris tardigradus Osphranter rufus Micaelamys namaquensis Hemiechinus auritus Eidolon helvum Cyclopes didactylus Ellobius talpinus Monodelphis domestica Pteropus pumilus Tamias amoenus Varecia rubra Odocoileus virginianus Lemur catta Cavia porcellus Pteropus vampyrus Apodemus sylvaticus Paraechinus hypomelas Pteropus poliocephalus Microtus ochrogaster Paraechinus aethiopicus Sorex palustris Nanger soemmerringii Alticola semicanus Zalophus californianus Ornithorhynchus anatinus Vicugna pacos Xanthonycticebus pygmaeus Cricetulus longicaudatus Plecotus auritus Otolemur crassicaudatus Litocranius walleri Orientallactaga sibirica Panthera leo Arvicanthis niloticus Carollia perspicillata Eptesicus fuscus Pteropus rodricensis Phoca groenlandica Tamiasciurus hudsonicus Rousettus aegyptiacus Phoca vitulina Eulemur coronatus Peromyscus californicus Sorex roboratus Elephantulus myurus Bathyergus janetta Gerbillus nanus Lynx rufus Caenolestes fuliginosus Nyctalus noctula Osphranter robustus Mops pumilus Gorilla gorilla Hylomys suillus Tamiasciurus douglasii Panthera tigris Sarcophilus harrisii Myotis myotis Propithecus coquereli Mesoplodon bidens Phascolarctos cinereus Didelphis marsupialis Fukomys damarensis Asellia tridens Microgale thomasi Apodemus uralensis Aplodontia rufa Mustela putorius furo Equus grevyi Sorex isodon Sagmatias obliquidens Antrozous pallidus Peromyscus polionotus Hippotragus niger Tamias striatus Balaena mysticetus Nanger dama Condylura cristata Meriones rex Hipposideros ruber Macaca mulatta

PROVIDER: GSE223748 | GEO | 2023/08/05

REPOSITORIES: GEO