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RNA-Seq profiles of pancreatic adenocarcinoma PANC-1 and osteosarcoma U2OS cells with Pin1 knocking down

ABSTRACT: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) mediates conformational conversion of protein substrates to trigger the modulation of protein phosphorylation status. Pin1 was knockdown in the pancreatic adenocarcinoma cell PANC-1 and osteosarcoma cell U2OS. The expression profiles of them were compared to explore the key features regulated by Pin1.

ORGANISM(S): Homo sapiens

PROVIDER: GSE224502 | GEO | 2025/02/02

REPOSITORIES: GEO

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Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3' processing and transcription termination that functions via its effects on CTD phosphatase Ssu72

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