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Polycomb Repressive Complex 2 regulates basal cell fate during adult olfactory neurogenesism [scRNA-seq]

ABSTRACT: We show that Polycomb repressive complexes (PRCs) regulate lineage choice between neural and non-neural fates in the olfactory epithelium. Conditional loss of Polycomb repressive complex 2 perturbs lesion-induced neurogenesis and misexpression of lineage-specific transcription factors in multipotent olfactory globose basal cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE224893 | GEO | 2023/09/18

REPOSITORIES: GEO

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