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In vitro Naïve B-cell Class Switching Stimulation with ATM-inhibitor and DNA-PKcs-inhibitor

ABSTRACT: Analyze Class switch recombination of naïve B-cells in vitro mimicking Ataxia Telangiectasia using a small molecule inhibitor (KU-55933). We measure switched IgG and IgG memory B-cells, and analyzed transcriptomics (this data).

ORGANISM(S): Homo sapiens

PROVIDER: GSE225461 | GEO | 2024/05/21

REPOSITORIES: GEO

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