Transcriptomics

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NGS analysis of T-ALL cell lines treated with mTORC1 inhibitor


ABSTRACT: We recentlly showed that everolimus, a mTORC1 inhibitor increases reactive oxygen species (ROS) levels, decreases the levels of NADPH and of glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the pentose phosphate pathway (PPP), and induces apoptosis of T-ALL cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE225751 | GEO | 2023/02/23

REPOSITORIES: GEO

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