NGS analysis of T-ALL cell lines treated with mTORC1 inhibitor
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ABSTRACT: We recentlly showed that everolimus, a mTORC1 inhibitor increases reactive oxygen species (ROS) levels, decreases the levels of NADPH and of glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the pentose phosphate pathway (PPP), and induces apoptosis of T-ALL cells.
ORGANISM(S): Homo sapiens
PROVIDER: GSE225751 | GEO | 2023/02/23
REPOSITORIES: GEO
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