Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [Ser2PRNAPII ChIP-seq]
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ABSTRACT: To investigate changes in the elongating form of RNA Polymerase II across different conditions, we peformed ChIP-seq using antibody against the Ser2P RNAPII of pTEFb in K562 cells at 4 days after modified allele expression We then performed coverage plot analyses using data obtained from ChIP-seq from IP and Input fractions to investigate Ser2P RNAPII distribution changes
ORGANISM(S): Homo sapiens
PROVIDER: GSE225995 | GEO | 2024/03/12
REPOSITORIES: GEO
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