Other

Dataset Information

0

Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [GRO-seq]


ABSTRACT: To investigate redistribution of RNAPII in response to the SF3B1 mutation and to study its effects on nascent gene expression, we peformed fastGRO-seq (variant of GRO-seq using 4-thio-UTP based nuclear run-on) in K562 cells (wild type and SF3B1K700E mutant) at 4 days after mutant allele expression We then performed metaplot-based and gene expression analysis using data obtained from fastGRO-seq

ORGANISM(S): Homo sapiens

PROVIDER: GSE225999 | GEO | 2024/03/12

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-03-12 | GSE225997 | GEO
2024-03-12 | GSE225996 | GEO
2024-03-12 | GSE254793 | GEO
2024-03-12 | GSE225992 | GEO
2024-03-12 | GSE226000 | GEO
2024-03-12 | GSE226001 | GEO
2024-03-12 | GSE226002 | GEO
2024-03-12 | GSE225998 | GEO
2024-03-12 | GSE254792 | GEO
2016-08-17 | GSE85712 | GEO