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PFG controls gene expression in female gametocytes cooperatively with AP2-FG [AP2-FG_DIP]

ABSTRACT: AP2-FG is a female-specific transcription factor (TF) that plays an essential role in female gametocyte development. AP2-FG activates hundreds of genes by binding to a female-specific ten-base cis-acting element. Here, we report that in the rodent malaria parasite Plasmodium berghei, another female-specific TF designated as a partner of AP2-FG (PFG), controls gene expression in female gametocytes cooperatively with AP2-FG. Transcriptional mechanisms were analyzed in Plasmodium berghei female gametocytes.

ORGANISM(S): Plasmodium berghei

PROVIDER: GSE226020 | GEO | 2024/01/22

REPOSITORIES: GEO

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PFG controls gene expression in female gametocytes cooperatively with AP2-FG [PFG_ChIP-seq]

Project description:AP2-FG is a female-specific transcription factor (TF) that plays an essential role in female gametocyte development. AP2-FG activates hundreds of genes by binding to a female-specific ten-base cis-acting element. Here, we report that in the rodent malaria parasite Plasmodium berghei, another female-specific TF designated as a partner of AP2-FG (PFG), controls gene expression in female gametocytes cooperatively with AP2-FG. Transcriptional mechanisms were analyzed in Plasmodium berghei female gametocytes.

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PFG controls gene expression in female gametocytes cooperatively with AP2-FG

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