Transcriptomics

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Effects of 3-HAA on HCC by regulating the heterogeneous macrophages—A single-cell RNA-seq analysis


ABSTRACT: CyTOF data showed that 3-HAA significantly increased the percentage of F4/80hiCX3CR1loKi67loMHCIIhi macrophage and decreased the percentage of F4/80loCD64+PD-L1lo macrophages. scRNA-seq analyses demonstrated that 3-HAA administration was proved to regulate the function of M1 macrophages, M2 macrophages, and proliferating macrophages.

ORGANISM(S): Mus musculus

PROVIDER: GSE226510 | GEO | 2023/06/07

REPOSITORIES: GEO

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